stability studies play a critical role in assuring product quality at all points in the vaccine life cycle. these studies used to determine vaccine expiry date and vaccine efficacy. accelerated stability and long term stability study performed for three batches of trivalent oral poliomyelitis vaccine (opv) and three batches of monovalent opv (type1) manufactured by razi institute. after samplin...

INTRODUCTION The aim of this study was to compare the effect of subcutaneously implanted white mineral trioxide aggregate (WMTA) on inflammatory reactions before and after expiry date. METHODS Fifty Wistar rats were used in this study. Polyethylene tubes were filled with WMTA with expiry dates of 2008, 2009, and 2011, and empty ones serving as the controls were implanted into the subcutaneous...